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EZR-ROS1/BaF3

CBP73324

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I. Introduction    

Cell Line Name:

EZR-ROS1/BaF3

   

Host Cell:

Ba/F3

   
Stability: 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)    

Application:

Anti-proliferation assay and PD assay

   

Freeze Medium:

90% FBS+10% DMSO

   

Complete Culture Medium:

RPMI-1640+10%FBS

   

Mycoplasma Status:

Negative

   
     
II. Background    
EZR, ezrin, is a member of the ERM family that links the cytoplasm to the actin cytoskeleton and regulates polarization and migration in leukocytes and macrophages. EZR plays a role in metastasis in a number of cancer types although decreased Ezr expression has been associated with decreased survival in clear cell renal carcinoma and an EZR-ROS1 fusion has been identified in lung cancer.    
     
III. Representative Data    

1.Sanger of EZR-ROS1/BaF3

   

2. Anti-proliferation assay

Figure 2. CTG Proliferation Assay of BaF3 EZR-ROS1 (C5).

   
     
     

 

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