pCBRG- STAT1::STAT1 RE
CBV20068
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| Introduction | |
| Description: | pSTAT1:STAT1 RE-Luc is designed for monitoring the induction of Signal transducer and activator of transcription 1.Signal transducer and activator of transcription 1 (STAT1) is a transcription factor which in humans is encoded by the STAT1 gene. It is a member of the STAT protein family.STAT1 is involved in upregulating genes due to a signal by either type I, type II, or type III interferons. In response to IFN-γ stimulation, STAT1 forms homodimers or heterodimers with STAT3 that bind to the GAS (Interferon-Gamma-Activated Sequence) promoter element; in response to either IFN-α or IFN-β stimulation, STAT1 forms a heterodimer with STAT2 that can bind the ISRE (Interferon-Stimulated Response Element) promoter element. |
| Plasmid profile: |  |
| Unit Size: | 1-4μg |
| Pathway (Activitor): | Type II Interferon |
| Pathway profile: |  |
| Full Name: | Signal transducer and activator of transcription 1 |
| Cis response element: | STAT1:STAT1 RE |
| Shelf Life: | One year from date of receipt under proper storage conditions. |
| Storage: | -20°C |
| Mode of transportation: | Ice bag transport |
| Matters needing attention: | For your health, please wear lab clothes and disposable gloves. |
