pCBRG- TFEB RE
CBV20069
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| Introduction | |
| Description: | pTFEB RE-Luc is designed for monitoring the induction of Transcription factor?EB.TFEB is a master gene for lysosomal biogenesis.It encodes a transcription factor that coordinates expression of lysosomal hydrolases, membrane proteins and genes involved in autophagy.Upon nutrient depletion and under aberrant lysosomal storage conditions such as in lysosomal storage diseases, TFEB translocates from the cytoplasm to the nucleus, resulting in the activation of its target genes. |
| Plasmid profile: |  |
| Unit Size: | 1-4μg |
| Pathway (Activitor): | Lysosomal biogenesis (ERK2) |
| Pathway profile: |  |
| Full Name: | Transcription factor?EB |
| Cis response element: | TFEB RE |
| Shelf Life: | One year from date of receipt under proper storage conditions. |
| Storage: | -20°C |
| Mode of transportation: | Ice bag transport |
| Matters needing attention: | For your health, please wear lab clothes and disposable gloves. |
